Dnmt3 and G9a Cooperate for Tissue-specific Development in Zebrafish
نویسندگان
چکیده
منابع مشابه
Dnmt3 and G9a Cooperate for Tissue-specific Development in Zebrafish*
Although DNA methylation is critical for proper embryonic and tissue-specific development, how different DNA methyltransferases affect tissue-specific development and their targets remains unknown. We address this issue in zebrafish through antisense-based morpholino knockdown of Dnmt3 and Dnmt1. Our data reveal that Dnmt3 is required for proper neurogenesis, and its absence results in profound...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2010
ISSN: 0021-9258
DOI: 10.1074/jbc.m109.073676